Introduction: Ischemic heart disease ranked among
the leading causes of death worldwide. Several biological and genetic risk
factors associated with acute coronary syndrome. By addressing the risk factors, it is possible to prevent most of the
cardiovascular diseases and contribute to the reduction of complications of
acute coronary syndrome. Material and Methods: Our study is a prospective study
that was conducted to the main military hospital of instruction of Tunis.
Recruitment involved 122 coronary (n = 122) and 705 controls (n = 705) totaling
a population of 827 subjects. Data collection concerned socio-demographic
characteristics, anthropometric measurements, habits and lifestyle, health
status and biological assessment. Results: Our study reported a high prevalence
of cardiovascular classic risk factor particularly overweight (62.3%), diabetes
(63.1%) and hypertension (50%). In 55% of coronary patients, moderate to intermediate
hyperhomocysteinemia was found, but it appears to be an independent risk
factor. The results of our study show a significant difference in the genotypic
frequencies of the C677T mutation in the MTHFR gene between the two populations,
cases and controls. Conclusion: Acute coronary syndromes are the leading cause
of sudden death in adults. The evaluation of risk factors after acute coronary
syndrome episode is essential for a better management according to the
recommendations of learned societies and standards of good practice.
Cite this paper
Nadra, G. , Rihab, S. , Ossama, L. , Sana, A. , Manel, A. , Mabrouka, E. O. , Najla, S. , Thaker, L. , Habib, H. , Chakib, M. and Zied, A. (2018). Evaluation of Cardiovascular Risk Factors in Tunisian Coronary Patients. Open Access Library Journal, 5, e4214. doi: http://dx.doi.org/10.4236/oalib.1104214.
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