Bacterial resistance to
pharmaceutical drugs is on rise, which emphasizes the need for screening of new drugs from
natural resources. Seaweeds from the marine ecosystem are important source of
bioactive compounds making them one of the major subjects for screening of various
pharmaceutical drugs. So here, we assessed the bacterial growth inhibitory functions of four seaweeds Sargassum wightii, Gracillaria edulis, G.
corticata and Ulva lactuca of
Andaman Sea and Bay of Bengal, India respectively against three pathogens Pseudomonas aeruginosa, Eischeira coli and Staphylococcus aureus. Solvent extraction of four seaweeds was
performed using 70% methanol, ethanol and ethyl acetate. Agar well diffusion
method was used to test the bioactivity of seaweeds against pathogens. S. wightii, G. edulis and U. lactuca were observed with better solvent extracts compared to G. corticata. Methanol extract of S. wightii was observed with the highest (29.0 ± 1.22) zone of inhibition (ZOI)
and ethyl acetate extract of U. lactuca was observed with the lowest ZOI (5.0 ± 0.0) against S. aureus. Butanol
extract of S. wightii was observed
with the highest ZOI (14.0 ± 0.83) against P. aeruginosa,
whereas G. edulis methanol extract
and U. lactuca ethyl-acetate extract
were observed with the lowest ZOI (6.0 ± 0.0). For E. coli, butanol and methanol extracts
of G. edulis and U. lactuca showed the highest (12.0 ± 0.54) and the lowest (6.0 ± 0.0). Our preliminary results
suggest bioactivity of S. wightii, G. edulis and U. lactuca showed positive results. Further biochemical
characterization of S. wightii should
be carried out for potential bioactive compounds against human pathogens. Our
results suggest bioactive compounds from seaweeds can be used as pharmaceutical
Cite this paper
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