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Further Thoughts on Abnormal Chromatin Configuration and Oncogenesis

DOI: 10.4236/oalib.1105185, PP. 1-5

Subject Areas: Molecular Biology, Cell Biology, Developmental Biology, Genomics

Keywords: Chromatin Configuration, Oncogenesis, 3D Genome, Cancer, Cell Differentiation, Cell Cycle, Gene Regulation, Gene Activity

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Abstract

More than 30 years ago, we published a paper entitled as “Abnormal Chromatin Configuration and Oncogenesis”, which proposed the first hy-pothesis that links oncogenesis to abnormal three-dimensional (3D) genome structure. Recently, many studies have demonstrated that the 3D genome structure plays a major role in oncogenesis, which strongly supports our hypothesis. In this paper, further thoughts about our hypothesis are presented.

Cite this paper

Li, G. (2019). Further Thoughts on Abnormal Chromatin Configuration and Oncogenesis. Open Access Library Journal, 6, e5185. doi: http://dx.doi.org/10.4236/oalib.1105185.

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