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Jun 21, 2018Open    AccessArticle

Etiological Profile of Patients Presenting with Lower Gastrointestinal Bleeding in Ibb Governorate-Yemen

Abdulgafoor Kassim, Khalid Al-Qubaty, Ramea Alathwary, Sana Ameen
Objectives: To investigate the causes of lower gastrointestinal bleeding (LGIB) in Yemeni patients and to compare our results with the results of other studies. Design: Prospective study of patients with overt LGIB during the period from April 2017 to March 2018. Setting: Specialized center of gastrointestinal and liver diseases in Ibb city, Yemen. Subjects & Method: Consecutive patients who presented or referred to our center
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Mar 07, 2018Open    AccessArticle

Clinicopathological Pattern of Gastric Cancer of Yemeni Patients in Ibb Governorate

Abdulgafoor Kassim, Mohammed Al-Qubaty, Fayed Al-Yousofy, Ramea Alathwary, Sana Ameen
Objectives: To study the clinicopathological pattern of gastric cancer in-cluding the location of the tumor in the stomach and to compare our results with other studies. Design: Prospective study of patients confirmed with gastric malignancy during the period from July 2016 to July 2017. Setting: Specialized center of gastrointestinal and liver diseases in Ibb city, Yemen. Subjects: All patients with histopath
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Nov 30, 2017Open    AccessArticle

Laparoscopic Abdominoperineal Resection for Low Rectal Cancer at National Cancer Hospital of Vietnam

Binh V. Pham, Anh T. Pham, Su Bin Kim, Tran Van Thuan, Nguyen Tien Quang
Introduction: Results of laparoscopic colectomies from developing nations are reported rarely. We report our results of laparoscopic abdominoperineal resec-tion (LAPR) for low rectal cancer at K Hospital (National Cancer Hospital of Vietnam). Materials & Methods: From January 2012 to December 2015, a to-tal of 135 patients who were diagnosed with low rectal adenocarcinoma were recruited to evaluate for LAPR surgical outcome perfor
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Jan 05, 2017Open    AccessArticle

Goblet Cell Carcinoid Tumors of the Appendix: A Report of Two Cases, Review of a Rare Clinical Entity, and Guidelines for Treatment

Carlos Alvarez-Laso, Enedina Azcano, Juan F. Carrion, Diana Rodríguez, José R. Riera
Goblet cell carcinoid tumor is a rare clinical entity which is usually diagnosed either as acute appendicitis or advanced cancer. Its main characteristic is that the histological findings are between those of adenocarcinoma and typical carcinoid tumor of the appendix. Goblet cell carcinoid tumors appear almost exclusively in the appendix, and prognosis depends mainly on the stage and the subtype of the histological classification.
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Nov 24, 2016Open    AccessArticle

Experimental Model with Choledochojejunostomy in Rats—Technique and Significance

Naoki Hashimoto, Shigeaki Yamanaka, Haruhiko Imamoto
A simple technique of choledochojejunostomy in rats is introduced in this paper and its suitability for use is as an experimental model. The healing characteristics of sutureless choledochojejunostomy rat (C-J rat) were investigated in a rat experimental model. The common bile duct of 10 conditioned Wistar rats was exposed, divided transversely and a choledochojejunostomy constructed with only a vinyl chloride tube positioned betw
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Jun 08, 2016Open    AccessArticle

Pattern of Upper Gastrointestinal Malignancies as Seen at Endoscopy in Ekiti State University Teaching Hospital, Ado-Ekiti, Nigeria

Akande Oladimeji Ajayi, Ebenezer Adekunle Ajayi, Olusoji Abidemi Solomon, Emmanuel Abidemi Omonisi, Samuel Ayokunle Dada
Aims and Objective: Gastrointestinal malignancies are among the most lethal of all malignancies and are equally notorious for rapidly progressing to advanced stages even in the absence of serious symptoms, thus leading to delayed diagnoses and dismal prognoses. The aim of this study was to determine the prevalence, type, pattern and the histologic characteristics of upper gastrointestinal tumors seen in patients who underwent uppe
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May 27, 2016Open    AccessArticle

Top-Down Research, Generalists, and Google Scholar: Does Google Scholar Facilitate Breakthrough Research?

Yellowlees Douglas
Researchers long ago demonstrated that top-down, inference-based approaches to research have comfortably co-existed with more traditional bottom-up, hypotheses-driven research. Yet most faculty omit any mention of top-down approaches in direct instruction or training of students, despite these approaches being both relatively common, occasionally necessary, and considerably more efficient than traditional bottom-up research. The g
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Jan 22, 2016Open    AccessArticle

Prevention and Management of Periampullary Tumors in Familial Adenomatous Polyposis

Naoki Hashimoto
Familial adenomatosis polyposis (FAP) is one of two well described forms of hereditary colorectal cancer. The primary cause of death from this symdrome is colorectal caner which develops usually by the fifth decade of life. The overall survival of FAP was significantly improved by screening by genetic testing and endoscopy with prophylactic surgery. Almost all patients with FAP develop duodenal polyposis most of which occurs in periampullary. The second leading cause of death in FAP is duodenal ...


Jun 04, 2015Open    AccessArticle

Adherence to American Association for the Study of Liver Diseases (AASLD) Guidelines and Predictors of Readmission in Cirrhotic Patients: A Single Center Experience

Maen M. Masadeh, Ali Zaied, Feroze Hussain, Heidi Spratt, Roger Soloway
Introduction: Liver cirrhosis (LC) is a major cause of mortality and morbidity in the United States. American Association for the Study of Liver Disease (AASLD) has developed guidelines for the management of patients with LC. Methods: We conducted a one-year retrospective chart review study of patients admitted with LC related complication. Our primary outcome was adherence to AASLD guidelines for the management of variceal bleeding (VB), fluid overload and hepatocellular carcinoma (HCC) screeni...


Feb 05, 2015Open    AccessArticle

Protective Effect of Ischemic Preconditioning on Hepatic Ischemia-Reperfusion Injury in Rats

Naoki Hashimoto
Aim: Ischemic preconditioning (IPC) protects tissue against ischemia and reperfusion (I/R) injury. The aim of this study was to examine the impact of IPC on protection of hepatocytes after prolonged I/R injury. Methods: Twenty-four Wistar rats were randomly divided into ischemic preconditioning group (IP), ischemia/reperfusion group (IR) and sham operation group (SO). A model of partial liver ischemia/reperfusion was used, in which rats were subjected to liver ischemia for 90 min prior to reperf...


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