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OALib Journal期刊

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Frequency and Causes of Vaginal Hemorrhage outside Pregnancy in Women of Reproductive Age at Bonzola Hospital, Mbuji-Mayi, DRC  [PDF]
Kaya Tompa Brigitte, Ciamala Mukendi Paul, Nzembu Kabwasa Peter, Kanyiki Katala Moses, Ntumba Mukendi Kennedy, Jean Mukendi Mukendi Rene, Kolela Kolela Alain, Ilunga Bimpa Cedric, Cibangu Muana Wamuenyi Franck, Kaseka Ciswaka Jeanne, Amuli Jiwe Jean-Pierre
Open Access Library Journal (OALib Journal) , 2018, DOI: 10.4236/oalib.1104940
Abstract:
Vaginal haemorrhages outside pregnancy in women of childbearing age are a major public health problem in both developed and developing countries. The purpose of this study was to determine the frequency and causes of vaginal haemorrhage outside pregnancy. This is a descriptive study conducted in the city of Mbuji-Mayi at Bonzola General Hospital, registered from 01 to 31 December 2017; the data were collected transversally. The following observations were made during the study period; 174 women of childbearing age were registered. After analyzing the data, the incidence of vaginal haemorrhage in women of childbearing age was 15.8% and the main causes were: cervical cancer: 32.7% and uterine myoma 22.5%.
Volatility Forecasting of Market Demand as Aids for Planning Manufacturing Activities  [PDF]
Jean-Pierre Briffaut, Patrick Lallement
Journal of Service Science and Management (JSSM) , 2010, DOI: 10.4236/jssm.2010.34045
Abstract: The concepts and techniques designed and used for pricing financial options have been applied to assist in scheduling manufacturing activities. Releasing a manufacturing order is viewed as an investment opportunity whose properties are similar to a call option. Its value can be considered as the derivative of the market demand mirrored in the selling price of the manufactured products and changes over time following an Itô process. Dynamic programming has been used to derive the optimal timing for releasing manufacturing orders. It appears advisable to release a manufacturing when the unit selling price come to a threshold P* given by the relation P* = β/(β–1) C with C = unit cost price. β is a parameter whose value depends on the trend parameter α and the volatility σ of the selling price, the discount rate ρ applicable to the capital appreciation relevant to the business context under consideration. The results have been successfully applied to the evolution of the quarterly construction cost index in France over ten years.
Chaos Appearance during Domain Wall Motion under Electronic Transfer in Nanomagnets  [PDF]
Donfack Gildas Hermann, Jean-Pierre Nguenang
World Journal of Condensed Matter Physics (WJCMP) , 2013, DOI: 10.4236/wjcmp.2013.33022
Abstract:

In this paper, we study the likelihood of chaos appearance during domain wall motion induced by electronic transfer. Considering a time-varying current density theory, we proceed to a numerical investigation of the dynamics. Using the dissipation parameter, amplitude and frequency of current density as control parameters; we show how periodic regime as well as chaotic regime can be exhibited in nanomagnetic systems. Numerical results allow setting up the periodicity and quasi-periodicity of system and chaotic phenomena occurring during magnetization switching process in nanomagnet through electronic transfer.

Traceability in Acceptance Testing  [PDF]
Jean-Pierre Corriveau, Wei Shi
Journal of Software Engineering and Applications (JSEA) , 2013, DOI: 10.4236/jsea.2013.610A005
Abstract:

Regardless of which (model-centric or code-centric) development process is adopted, industrial software production ultimately and necessarily requires the delivery of an executable implementation. It is generally accepted that the quality of such an implementation is of utmost importance. Yet current verification techniques, including software testing, remain problematic. In this paper, we focus on acceptance testing, that is, on the validation of the actual behavior of the implementation under test against the requirements of stakeholder(s). This task must be as objective and automated as possible. Our first goal is to review existing code-based and model-based tools for testing in light of what such an objective and automated approach to acceptance testing entails. Our contention is that the difficulties we identify originate mainly in a lack of traceability between a testable model of the requirements of the stakeholder(s) and the test cases used to validate these requirements. We then investigate whether such traceability is addressed in other relevant specification-based approaches.

DNA Nano Devices as a Biased Random Walk Process: A Case Study of Isothermal Ratchet?  [PDF]
Jean-Pierre Aimé, Juan Elezgaray
Materials Sciences and Applications (MSA) , 2015, DOI: 10.4236/msa.2015.65045
Abstract: Computation and amplification processes based on Networks of Chemical Reactions are at the heart of our understanding of the regulation and error correction of life systems. The recent advances in DNA nanotechnology, with the creation of the modular structures origamis and the development of dynamical networks using the toe hold mediated strand displacement, open fertile areas to construct Hierarchical Cascades of Chemical Reactions with an increasing complexity inspired from systems in biology. DNA strands have the great advantage to design autonomous and homogeneous Networks of Chemical Reactions leaving aside companion chemical reactions as it occurs in biological systems. In the present paper, we use the Fokker Planck equation to extract predictions that address a wider class of systems beyond the case of diluted solutions. We introduce the concept of toehold strength and output strength that leads to an exponential square dependence of the toehold strength divided by the output strength on the escape rate and the probability for the output strand to leave the gate. We highlight the influence of the boundary conditions that may have an important consequence in confined environment when modular structures like origamis are employed.
Skeletal involvement in the pathogenesis and outcomes of rheumatoid arthritis and osteoarthritis
Jean-Pierre Pelletier
Arthritis Research & Therapy , 2012, DOI: 10.1186/ar3571
Abstract: In RA, increased osteoclastic activity is responsible for the development of focal osteopenia/erosion and systemic osteoporosis. The increased osteoclast activity in RA has been demonstrated to be linked to a dysregulation of pathways including cell-cell interactions, cytokines, and the receptor activator of nuclear factor κB (RANK)/RANK ligand (RANKL) system. Recent studies have shown that joint erosion in RA is linked to a decrease in long-term physical function.Under OA conditions, the subchondral bone is the site of numerous dynamic morphological changes. These changes are associated with a number of local abnormal biochemical pathways related to the altered metabolism of osteoblasts and osteoclasts. At the early stages of the disease process, increased bone loss and resorption is observed with subchondral bone associated with local production of catabolic factors including cathepsin K and MMP-13. Moreover, OA osteoblasts present an abnormal phenotype resulting in increased production of growth hormones and catabolic factors. In addition, factors such as osteoprotegerin (OPG) and RANKL have been found to be expressed and modulated over time in human OA subchondral bone. Their synthesis varies from being reduced in early OA to being increased in the late stages of the disease. This finding may explain that in the early stages of OA, bone remodeling favors resorption and in the more advanced stages of the disease, bone formation is predominant.Magnetic resonance imaging (MRI) studies in knee OA patients have shown that the subchondral bone is frequently the site of signal alterations-bone marrow lesions (BML) - indicative of a great variety of morphological changes. BML and cartilage loss have been linked in several studies. Moreover, studies have identified, in OA patients, a number of risk factors for total knee replacement including BMLs.The paradigms regarding the role of bone lesions in arthritic diseases raise a number of important questions. A comprehensive
rich: An R Package to Analyse Species Richness
Jean-Pierre Rossi
Diversity , 2011, DOI: 10.3390/d3010112
Abstract: The paper describes rich, a new R package to perform species richness estimation and comparison. Species richness is the simplest surrogate for the more complex concept of species biodiversity. It is relatively easy to assess although estimations strongly depend on sampling intensity with the consequence that richness estimations should be standardized to perform valid comparisons. The R package rich allows such corrections as well as the computation of various statistics and implements different randomization tests to compare cumulative and average species richness of two communities. These tests are useful for ranking sites or communities which is a classical goal in restoration ecology and conservation biology.
Supramolecular Bioorganic Chemistry: Nucleic Acids Recognition and Synthetic Vectors for Gene Transfer
Jean-Pierre Vigneron
Molecules , 1999, DOI: 10.3390/40700180
Abstract: Our works on nucleic acids recognition and synthetic vectors for gene transfer have been reviewed.
Os efeitos de uma "educa??o total": um colégio jesuíta, 1960
Faguer, Jean-Pierre;
Educa??o & Sociedade , 1997, DOI: 10.1590/S0101-73301997000100002
Abstract: this article is based on a monographic study of a school founded by the jesuits in the 16th arrondissement of paris, whose clientele is drawn mainly from the business bourgeoisie and the aristocracy. in particular it studies the teaching methods applied and the professional and family trajectories, the matrimonial strategies, and the division of family work between spouses of those graduating from the school with the baccalauréat in 1961. it also seeks to show how certain private schools can be seen as substitutes for family authority, charged with transmitting a model of education that is made more homogeneous by the fact that the parents share with the teachers the same conception of the role of the family and the school; and that these schools keep their pupils away from all contact with children from other social classes, not only during teaching time but also (it is one of the "specialities" of this kind of school) during most of the leisure activities for which they are responsible.
La dive bouteille: voyages, alcools et remèdes dans les deux hémisphères XVIe-XXe siècle
Goubert, Jean-Pierre;
História, Ciências, Saúde-Manguinhos , 2001, DOI: 10.1590/S0104-59702001000500008
Abstract: grace à l'analyse de la pratique médicale en france (bretagne), au canada et au brésil, on s'aper?oit que l'antique tradition de consommer du vin en tant que remède est présente dans le cadre de paradigmes scientifiques distincts et d'aires culturelles différentes entre xvie et xxe siècle. l'effet réputé protecteur de l'alcool, à condition que son usage soit modéré, avant qu'il soit prouvé scientifiquement par louis pasteur et par serge renaud, a figuré parmi les dogmes de la médecine humorale, qui associait les quatre principes fondateurs (le chaud et le froid, le sec et l'humide) avec diverses configurations environnementales et climatiques et avec l'age, le sexe, les m?urs et le physique. voyages et échanges entre métropoles et colonies contribuèrent à diffuser, pour ainsi dire, un discours médical à l'origine méditerranéenne dans les deux hémisphères.
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