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Different Protocols of Physical Training: Effect on Markers of Oxidative Stress in Erythrocytes in Rats  [PDF]
Marcelo Costa-Junior, Wener Barbosa-Resende, Michel Barbosa de Araújo, Rodrigo Augusto Dalia, Leandro Pereira de Moura, Luciana Alves de Medeiros, Lucas Moreira Cunha, Eliete Luciano
Open Access Library Journal (OALib Journal) , 2018, DOI: 10.4236/oalib.1104411
Abstract:
The imbalance between oxidant molecules and antioxidant agents is characterized as oxidative stress (OS) and may lead to severe damage to the organism. In contrast, the physical training of aerobic and resistive character promotes increases of the antioxidant response, resulting in a balance and/or minimizing damage. Therefore, the objective of the study is to verify the effect of aerobic training, resistive training and concurrent training on oxidative stress of Wistar rats. Methods: To perform the experiment, 40 Wistar rats were subjected to eight weeks of training. The animals were distributed into 4 different groups: control, aerobic, resistive and concurrent (combination of aerobic and resistive protocols in the same section) an h/day, five days/week, for eight weeks. At the end of the experimental period: the antioxidant enzymes (catalase, glutathione peroxidase and superoxide dismutase), biomarkers of oxidative stress (TBARs and H2O2) as well as the activity of reduced and oxidized glutathione were analyzed. Results: Regarding the markers, TBARs and H2O2 trainings were not effective in promoting significant reduction. In contrast, the three training protocols caused an increase in SOD and GSH-GPx enzymes. Conclusion: Therefore, we concluded that both training protocols promoted benefit to the organism, because they caused the increase of antioxidant enzymes without disturbance in the pro-oxidant markers.
Multiplex, megaplex, index, and complex: the present and future of laboratory diagnostics in rheumatology
Mark H Wener
Arthritis Research & Therapy , 2011, DOI: 10.1186/ar3498
Abstract: Multiplex diagnostic testing refers to the use of laboratory devices that perform many assays on the same specimen at the same time with a single laboratory platform. In some respects, autoimmune rheumatic disease tests have long involved multiplexing. For example, the immunofluorescence test for antibodies to nuclear antigens (ANAs) detects multiple ANA patterns and specificities. Modern multiplex methodology typically involves suspensions of antigen-coated microscopic beads that are distinguishable by physical characteristics such as fluorescent color. Research multiplex assays may employ planar arrays of antigens spotted on glass slides. Panels of automated multiplex clinical laboratory tests are available for autoantibody testing, such as testing for the specificities of ANAs. Multiplex research assays are widely used to test for cytokines and other biomarkers. In a recent issue of Arthritis Research & Therapy, Chandra and colleagues [1] explored the use of multiple multiplex assays (a 'megaplex'?) in the evaluation and categorization of patients with rheumatoid arthritis (RA).Implementing high-quality multiplexed protein assays has many technical analytical challenges, including problems of uniformity, cross-reactivity, and optimization [2,3]. Rheumatoid factors and other anti-reagent antibodies may interfere [4], as, indeed, they can interfere with individual immunoassays. Ideally, each individual assay included in the multiplex assay should be evaluated fully. Other criteria for evaluating reports of multiplex assays are suggested in Table 1.How should multiplex laboratory data be interpreted? When the biomarker number is small and their clinical value is understood, results can be sent to the provider directly for interpretation. However, access to multiple test results supports the creation of predictors that are more complex and hopefully more accurate, since they are based on the integrated results from more parameters.Diagnostic algorithms using multiple
Equidad y Empresas Públicas: Reflexiones Frente a los Casos de Brasil y Perú
Wener Baer,Adolfo Figueroa
Revista Economía , 1981,
Abstract: El artículo no presenta resumen.
Selection via simulated individual BLUP based on family genotypic effects in sugarcane
Resende, Marcos Deon Vilela de;Barbosa, Márcio Henrique Pereira;
Pesquisa Agropecuária Brasileira , 2006, DOI: 10.1590/S0100-204X2006000300008
Abstract: the objective of this work was to propose a new selection strategy for the initial stages of sugarcane improvement, based on the methodology 'simulated individual blup (blupis)', which promotes a dynamic allocation of individuals selected in each full-sib family, using blup as a base for both the genotypic effects of the referred families and plot effects. the method proposed applies to single full-sib families or those obtained from unbalanced or balanced diallel crosses, half-sib families and self-pollinated families. blupis indicates the number of individuals to be selected within each family, the total number of clones to be advanced, and the number of families to contribute with selected individuals. correlation between blupis and true blup was 0.96, by method validation. additionally, blupis allows the identification of which replication contains the best individuals of each family.
Quality of Seeds of Upland Rice Lines Adapted to the State of Minas Gerais, Brazil  [PDF]
Heloisa Oliveira dos Santos, Flávia Barbosa Silva Botelho, Ana Cláudia de Amorim Fonseca, Ricardo Kenji Uenojo, Marcela Pedroso Mendes, Edila Vilela de Resende Von Pinho
American Journal of Plant Sciences (AJPS) , 2015, DOI: 10.4236/ajps.2015.612193
Abstract: In the final stages of a plant breeding program, a crucial step is the multiplication of seeds in production fields. Besides a solid planning, the seeds multiplication needs a special attention to guarantee seeds with high quality, genetic integrity, high germination and vigor to the farmer. The aim of this study was to evaluate the physiologic quality, enzymatic expression and respiratory activity of seeds of 20 elite upland rice lines adapted to the state of Minas Gerais, Brazil, from the upland rice breeding program from three Brazilians research institutions. The quality parameters evaluated were root protrusion, number of normal seedlings in the germination test, number of normal seedlings in the germination first count, initial stand from emergence test, speed of emergence index, seedlings shoot and root length, percentage of O2 and CO2 from respiratory activity and the expression pattern of the enzymes alcohol dehydrogenase (ADH) and malate dehydrogenase (MDH). The seeds quality varied among lines, allowing the selection of lines with best performance. The respiratory activity was lower in seeds of lines with high quality. The enzyme ADH was an excellent marker to infer about the quality of seeds, and the variation in the expression of MDH did not depend on the quality of rice seeds. The lines BRS Esmeralda, CMG1896 and CMG1509 showed high physiologic quality in their seeds, and therefore, they should receive higher attention in rice breeding programs.
El análisis geométrico de encustas: la lección de La Distinción de Bourdieu
Rouanet Henry,Ackermann Wener,Le Roux Brigtte
Revista Colombiana de Sociología , 2001,
Abstract:
História da Geografia e Geografia Histórica: à procura dos híbridos
David Palacios,Marcelo Wener da Silva
Terra Brasilis : Revista da Rede Brasileira de História da Geografia e Geografia Histórica , 2012,
Abstract: Este primeiro número da Nova Série da Terra Brasilis – Revista da Rede Brasileira de História da Geografia e Geografia Histórica apresenta as potencialidades da nossa área de trabalho e a amplitude e versatilidade do leque das nossas preocupa es hibridas. Os artigos que apresentamos à continua o misturam em formas diferentes história do pensamento geográfico, história da cartografia, historia do ensino da geografia, história das institui es geográficas, geografia histórica, história urbana...
Imaging findings and cerebral perfusion in arterial ischemic stroke due to transient cerebral arteriopathy in children
Barbosa Junior, Alcino Alves;Ellovitch, Saada Resende de Souza;Pincerato, Rita de Cassia Maciel;
Einstein (S?o Paulo) , 2012, DOI: 10.1590/S1679-45082012000200021
Abstract: we report the case of a 4-year-old female child who developed an arterial ischemic stroke in the left middle cerebral artery territory, due to a proximal stenosis of the supraclinoid internal carotid artery, most probably related to transient cerebral arteriopathy of childhood. computed tomography scan, magnetic resonance imaging, perfusion magnetic resonance and magnetic resonance angiography are presented, as well as follow-up by magnetic resonance and magnetic resonance angiography exams. changes in cerebral perfusion and diffusion-perfusion mismatch call attention. as far as we know, this is the first report of magnetic resonance perfusion findings in transient cerebral arteriopathy.
Rea??es cutaneas secundárias ao uso dos inibidores do receptor de fator de crescimento epidérmico: relato de dois casos
Rodarte, Camila Martins;Abdallah, Omar Ali;Barbosa, Nadyesda Fagundes;Koch, Ludmila de Oliveira;Resende, Uirá Maira;
Anais Brasileiros de Dermatologia , 2009, DOI: 10.1590/S0365-05962009000600015
Abstract: an increase in the expression of epidermal growth factor receptors (egfr) is involved in the stimulation of tumor development. egfr inhibitors have shown efficacy in the treatment of neoplasms of the head, neck, colon and lung. egfr when inhibited can cause cutaneous reactions in more than 50% of the patients. they are usually reversible, but when severe, limit the use of the drug. papulopustulars lesions in the face and upper torso are the most common, as well as xerosis, hair and nail changes. there is a direct relationship between the degree of cutaneous toxicity and the antitumoral response. an adequate dermatologic approach is necessary for an effective therapy against cancer.
Estimativas de parametros genéticos e métodos de sele??o para o melhoramento genético de Pinus oocarpa Schiede
Sampaio, Paulo de Tarso Barbosa;Resende, Marcos Deon Vilela de;Araújo, Antonio José de;
Pesquisa Agropecuária Brasileira , 2002, DOI: 10.1590/S0100-204X2002000500007
Abstract: this work aimed to study the genetic variability within and between provenances and progenies and to determine the genetic gain related to timber volume, in pinus oocarpa. the experiment was carried up in angatuba, s?o paulo, brazil, in a compact family block design, with nine replications and six plant plots. the results of seven provenances showed a production of 0.296 m3 of timber per tree at nine years-old. to establish seedling seed orchard, 189 trees with the greatest genetic gain in diameter at breast height (27 trees per provenance) were selected. the selection of these trees will allow an increase in the current volumetric timber production, reaching 0.327 m3 per tree (individual selection), 0.338 m3 per tree (combined selection) and 0.341 m3 per tree (multi-effect index). to implement a clonal seed orchard, 28 trees with the greatest genetic gain in diameter at breast height (four trees per provenance) were selected. the selection of these trees will allow an increase in the current volumetric timber production, reaching 0.345 m3 per tree (individual selection), 0.355 m3 per tree (combined selection) and 0.356 m3 per tree (multi-effect index).
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