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Prevalence and Characteristics of Peripartum Cardiomyopathy among Women with Cadiac Failure Referred for Echocardiography in a Tertiary Hospital in Northern Nigeria  [PDF]
Hadiza Saidu, Abdulwahab Kabir, Nkem Ndiche, Jamila A. Yau, Umar Abdullahi, M. S. Mijinyawa
Journal of Biosciences and Medicines (JBM) , 2018, DOI: 10.4236/jbm.2018.63007
Abstract: Introduction: Peripartum cardiomyopathy (PPCM) is a common clinical condition in northern Nigeria. This study aimed to determine the prevalence and characteristics of PPCM among women with heart failure referred for echocardiography. Materials and Methods: This is a retrospective study of 401 women managed for heart failure referred for echocardiography between October 2016 and September 2017. Their reports were analyzed for demographic and echocardiographic parameters. Results: The mean age of the 401 individuals studied was 41.28 ± 16.25 years. The commonest cause of heart failure was PPCM, accounting for 256 (69.5%), followed by hypertension 79 (19.7%) and rheumatic heart disease (RHD) 24 (5.9%). Conclusion: PPCM is a common and important cause of heart failure among women in Northern Nigeria.
Topic: Echocardiographic Evaluation of Left Ventricular Systolic and Diastolic Function in Nigerians with Sickle Cell Disease  [PDF]
Hadiza Saidu, Abdulwahab Kabir, Jamila A. Yau, Ahmad M. Yakasai, Umar Abdullahi, Aisha M. Nalado, Baba Maiyaki Musa
Open Access Library Journal (OALib Journal) , 2018, DOI: 10.4236/oalib.1104527
Abstract:
Introduction: Sickle cell disease (SCD) is chronic, inherited haemoglobin disorder, associated with chronic tissue ischemia which may adversely affect any organ system. Chronic anaemia in SCD results in cardiac chamber dilatation with compensatory increase in left ventricular mass and varying degree of diastolic dysfunction that has been a strong independent predictor of mortality in patients with SCD. There is paucity of echocardiographic studies on adults Nigerians with SCD. This study therefore, aimed to assess left ventricular systolic and diastolic function among sickle cell disease patients in Kano State, North-Western Nigeria. Methods: The study was cross-sectional and comparative conducted at the SCD clinic and Medical/outpatient (MOP) clinic of Murtala Muhammad Specialist Hospital (MMSH), on eligible patients aged 13 years and above. One hundred patients with SCD (HbSS) were recruited as the study group while 100 non SCD (HbAA) patients, matched for age and sex served as controls. Left and right atrial and ventricular dimensions, left ventricular (LV) wall thickness, LV mass index and LV contractility variables were obtained. Parameters of LV diastolic function were also evaluated. Results: There were increases in the left atrial and left ventricular dimensions, left ventricular volumes and left ventricular mass (LVM) of the SCD patients. LV ejection fraction was equivalent, though there was evidence of left ventricular diastolic dysfunction in up to 36%. Conclusion: Left ventricular diastolic dysfunction may complicate cases adults with SCD.
The Role of Stability and Renegotiation in Transnational Petroleum Agreements
Hadiza Tijjani Mato
Journal of Politics and Law , 2012, DOI: 10.5539/jpl.v5n1p33
Abstract: Stability of existing agreements is the major means of investment protection at the disposal of multinational oil companies. This is achieved by inserting stabilization clauses to ensure that future changes in policy or legislation of the host country does not affect the existing agreement. Multinational oil companies are nevertheless confronted by the reality that stabilization clauses do not in fact provide the requisite immunity against host government action. On the part of host countries, it is recognized that their right to enjoy maximum benefits and to avoid adverse consequences from the exploitation of petroleum cannot be compromised on the ground that stability is an express term of the agreement. Therefore, renegotiation in the event of a fundamental change of circumstances surrounding the agreement appears to be a viable option for both parties to a petroleum agreement. Hence, this research examines the twin concepts of stability and renegotiation and their significance in international petroleum contracts.
Physicochemical features of rhodanese: A review
Y Saidu
African Journal of Biotechnology , 2004,
Abstract: Rhodanese is a multifunctional, mitochondrial, sulphur transferase that catalyses the detoxification of cyanide by sulphuration in a double displacement (ping pong) mechanistic reaction. It is widely distributed occurring in varieties of plants and animals, where it activity is modulated by a number of factors including differences in species, organs, sex, age and diet. The enzyme is a single polypeptide chain of 289 amino acids with molecular weight of up to 37,000. The active site of rhodanese contains a tryptophanyl residue in close proximity with an essential sulphahydryl group. Many methods for assaying rhodanese have been reported, the most prominent being the one based on the colorimetric estimation of thiocyanate formed from the reaction of cyanide and thiosulphate, catalysed by rhodanese.
Phytochemical Determinations and Antibacterial Activities of the Leaf Extracts of Combretum molle and Gossypium arboretum
TB Saidu, M Abdullahi
Bayero Journal of Pure and Applied Sciences , 2011,
Abstract: An investigation was carried out to screen the leaf extracts of Combratum mole and Gossypium arboreum for the presence of phytochemical components and antibacterial activity against Staphylococcus aureus strain OE5, Pseudomonas aeruginosa strain OE9, Klebsiella pneumoniae strain OE8 and Escherichia coli strain OE7 isolated from cases of otitis externa, using the agar diffusion procedure. The results indicated that the two medicinal plants contained alkaloids, tannins, saponins, anthracene, phenols and sesquiterpenes. Volatile oil was detected only in G. arboreum. The aqueous, ethanol and methanol extracts of the plants inhibited the growth of all the test organisms to varying degrees with the exception of E. coli, which was resistant to aqueous extract of C. mole. However, overall, the extracts of G.arboreum showed a higher degree of inhibition of the test bacteria than C.mole. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of G. arboreum and C.mole varied and ranged from 0.31mg/ml to 2.5mg/ml and 2.5mg/ml to 5.0mg/ml respectively. Synergistic effect of the ethanol and methanol extracts of the two plants resulted in enhanced antibacterial activity (large zones of inhibition, lower MIC, 0.31 – 1.25mg/ml, MBC, 0.63-2.5mg/ml).
Prevalence of Urinary Schistosomiasis among School Aged Children in Wushishi Local Government Area of Niger State, Nigeria
M Abdullahi, TB Saidu
Bayero Journal of Pure and Applied Sciences , 2011,
Abstract: An investigation was conducted to determine the prevalence of urinary Schistosomiasis in two localities namely,Wushishi and Zungeru of Wushishi local government of Niger State. Urine samples were collected from 100 school children of each of the two localities and investigated for eggs of Shistosoma haematobium using standard filtration techniques. The water contact activities of the inhabitants whose samples were collected were also obtained, using questionnaire method. Result obtained showed that 80 (40.0%) inhabitants were infected with a mean egg count. The infection rate was found to be higher among males (47.5%) than the females (28.75%) but the mean eggs count tend to be higher among the females (7.5 eggs/10ml of urine) than males (5.8 eggs/ml of urine). The results also showed that children aged 10 – 15 yrs old had the highest infection rate of 48.75% with 16.0 eggs/10ml of urine.
The Proximate and Elemental Analysis of some Leafy Vegetables Grown in Minna and Environs
AN Saidu, NG Jideobi
Journal of Applied Sciences and Environmental Management , 2009,
Abstract: Four different leafy vegetables grown and commonly consumed in Minna and it’s environ was analysed with a view to determine the nutrient content of these vegetables. The vegetables are water leaf ( Talinum triangulare), fluted pumpkin ( Telferia occidentalis), bitter leaf ( Vernonia amygdalina) and drumstick ( Moringa oleifera).Among the four leafy vegetables, Talinum triangulare contains the highest amount moisture (91.6%), Vernonia had the highest ash and lipid content (2.5%) and (0.7%) respectively. Moringa had the highest amount of protein (2.9%). It is also the richest source of sodium while Telfeiria had the highest K+ ion value. The results obtained in this work clearly indicates that the four leafy vegetables are cheap and readily available source of the nutrients.
A Review of Nigerian Metallic Minerals for Technological Development  [PDF]
Umar Saidu Bamalli, Ali Moumouni, Mohammed Suleiman Chaanda
Natural Resources (NR) , 2011, DOI: 10.4236/nr.2011.22011
Abstract: The metallic mineral resources of Nigeria have not been fully appraised due to lack of sufficient studies and technology. Previous works identified a number of minerals deposits which have remained largely unevaluated. Some known deposits were confirmed while new ones were identified and documented. The metallic minerals found in Nigeria include iron ore (with over 3 billion metric tonnes), ferro-alloy minerals (Manganese, vanadium, nickel, chromite, columbite, molybdenum, zircon, wolfram/tungsten tourmaline and tantalite), tin ore (cassiterite), lead/zinc, niobium, uranium ore and precious metal (Gold). Looking at the diversity of the mineral types and industrial importance of most of them and the need to exploit and process the minerals for technological development, there is need to build up capability to produce efficient unit operations of the required sizes by indigenous manufacturers.
Morphological characterization of indigenous and crossbred pigs in rural and peri-urban areas of southwestern Nigeria  [PDF]
Adeniyi Charles Adeola, Saidu O. Oseni, Ofelia Galma Omitogun
Open Journal of Animal Sciences (OJAS) , 2013, DOI: 10.4236/ojas.2013.33034
Abstract: We sought to determine morphological descriptors of Nigerian indigenous pigs (NIP) and crossbred pigs (CBP) based on relationships among live weight (LW) and a suite of 18 morphometric measurements plus the number of teats. We sampled four locations in southwestern Nigeria and obtained data for a total of 120 NIP and CBP. More female pigs (61.7%) than males (38.3%) were sampled, and they had a mean live weight of 19.9 ± 6.10 kg (range 9 - 32 kg) and 20.1 ± 6.08 kg (range 8 - 37 kg), respectively. The NIP had a longer snout, wider head and longer erect ears than CBP (P < 0.0001). Morphological variables that were highly correlated with LW included neck circumference (NC), breast height (BH), rump height (RH), body length (BL), interorbital width (IW), paunch girth (PG), hearth girth (HG), tail length (TL) and length of snout (LS) with Spearman correlation coefficients (R2) of 0.97, 0.92, 0.96, 0.97, 0.91, 0.97, 0.97, 0.90, and 0.93, respectively (all P < 0.0001). Teat number for NIP ranged from 5 to 14 while the CBP had a range of 10 to 16 teats. For male NIP, HG and TL best-fit in the model for body weight prediction (LW = ﹣25.71 + 0.43 HG + 2.21 TL; R2 = 0.93; P < 0.0001), while HG and IW had the best-fit for the female NIP (LW = ﹣28.27 + 0.50 HG + 2.22 IW; R2 = 0.96; P < 0.0001). Models for male and female CBP were LW = ﹣8.89 + 0.32 RH + 0.34 BL (R2 = 0.84; P < 0.0001) and LW = ﹣13.01 + 0.44 RH+0.27 BL (R2 = 0.94; P < 0.0001), respectively. Thus, for these populations of pigs, LS and TN differentiated NIP from CBP, because the NIP consistently recorded longer LS and lesser TN.
Analysis of Selenium Content in Root and Tuber Plants in Central Nigeria  [PDF]
Saidu Zarmai, Ishaq S. Eneji, Rufus Sha’Ato
American Journal of Analytical Chemistry (AJAC) , 2013, DOI: 10.4236/ajac.2013.412089
Abstract:

Some common staple roots and tubers (cassava, yam, sweet potato and yellow yam) were analyzed for selenium content level using hydride generation—atomic absorption spectrophotometry (HG-ASS) technique. Results for duplicate analysis revealed that sweet potato has the highest mean selenium content (19.2 ± 5.20 μg/kg), followed by yellow yam (18.3 ± 6.97 μg/kg), then yam (13.6 ± 7.12 μg/kg) and cassava the least (13.0 ± 5.84 μg/kg). In comparing our results with the literature values, most of the results obtained in this work such as <1.00, 1.09, 1.91, 2.35 and 11.0 μg/kg were lower while a few others like 52.6, 54.2, 72.3 and 81.8 μg/kg were higher than literature values. The variations could be due to the type of species/variety, geographical location, total selenium concentration in the soil and its bioavailability. In view of the importance of Se to human health and considering the levels found in the staples investigated, we recommend that sweet potato be popularized as a staple, much more than cassava as it is now the case in Central Nigeria.

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