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OALib Journal期刊

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Study of effects of aluminium chloride on histological structure of liver and spleen in pregnant rats and their offspring
Houriya MESTAGHANMI,Souad EL AMRANI,Imane M’TOUGUY,Rachid SAILE
Technologies de Laboratoire , 2011,
Abstract: Histological study of organs reflects the General State of animals, including, if they are subject to treatment. The purpose of our study is to elucidate the effect of the administration of different doses (50, 100 and 200 mg/Kg/day) of aluminum chloride during the days 9-13 of gestation on the histological structure of the liver and the spleen of pregnant rats and their offspring. In pregnant rats, AlCl3 leads, at the level of the liver, to a very important development of the connective tissue of the centrilobular vein, with inflammatory foci and hepatocyte injury. While at the level of the spleen, there is a development of the white pulp against the red pulp with an abundance of conjunctive fibres and dilation of the lining of arterioles, which reflects a failure of the circulatory system. The fetuses of rats treated by AlCl3, show no change in the histological structure of the spleen. The AlCl3 action is more marked than mothers in their fetuses. This certifies that the placenta forms a more or less selective barrier to some constituents, and that spleen in fetuses temporarily offset the effects of AlCl3
Breast Cancer in Men: Characteristics Epidemiological, Clinicopathological and Therapeutic  [PDF]
Ahmadaye Ibrahim Khalil, Houriya Mestaghanmi, Fadwa Qachach, Rachid Saile, Karima Bendahhou, Abdellatif Benider
Open Access Library Journal (OALib Journal) , 2016, DOI: 10.4236/oalib.1103166
Abstract:
Background: Breast cancer is the leading malignancy in women, but it is relatively rare in men, accounting for 1% of all breast cancers. In Morocco, its incidence is 0.8/ 100,000 in men. This condition epidemiology, therapeutic and prognostic remains unknown given the scarcity of reported series. The objective of this work is to identify the epidemiological, clinical, pathological and therapeutic of this cancer in men. Results: Six patients were diagnosed with breast cancer with a ratio of 6/1277 cases. The mean age of patients was 63.3 ± 9.7 ans; the most common histological type was invasive ductal carcinoma (83.3%). The grade 2 SBR has a majority (66.7%), while that of SBR 3 is less represented (33.3%). A positive estrogen receptor (66.7% of cases) and progesterone (50.0% of cases) was noted. The HER2 receptor is overexpressed in 25% of cases. The treatment was essentially surgical (83.3%). Additional treatment included adjuvant chemotherapy (50.0%), radiotherapy (50.0%) and hormonal therapy (16.7%) was administered. Discussion/Conclusion: Breast cancer in men is rare and appears to have a very close clinical, histological characteristics and prognosis to those of elderly women. The diagnosis is usually late and tumors are treated in advanced stages. An improved prognosis requires better awareness for early detection.
Survey of the Consumption of Energy Drinks and Frequency of Obesity in a Population of Academics from Casablanca  [PDF]
Imane M'Touguy, Nadia Iounes, Fatema Zehra Mahfoud, Marwa Chhail, Amine El Khatib, Rachid Saile, Souad El Amrani, Houriya Mestaghanmi
Open Access Library Journal (OALib Journal) , 2016, DOI: 10.4236/oalib.1103259
Abstract:
Background: An energy drinks supposed to give a boost of energy to the consumer. It usually contains caffeine and lot of sugar. We studied the risks associated with the consumption of these drinks, the conditions in which they are consumed and the frequency of obesity in the determination of body mass index among 195 students of the Faculty of Sciences Ben M’Sik. Methods: This is a survey conducted by students of the Ben M’sik Faculty of Sciences, Hassan II Casablanca University, during the year 2015, using a questionnaire exploring the consumption of energy drinks. Results: Our study shows 195 of surveyed students consuming energy drinks, of which 22.0% are girls and 78.0% are boys, of which 16.5% were overweight, 5.5% moderate and 2% severe obesity. 9.2% of students consume them to quench the thirst, 10.8% to bring their body energy, 7.7% for their taste, 21.5% to mitigate fatigue, 6.2% to stimulate and 44.6% for all the reasons cited. 4.6% say they associate them with tobacco, 4.0% with alcohol and 6.8% with some drugs during review periods. The consequences of poisoning these drinks can be serious health and manifest as tachycardia (3.2%), agitation or confusion (29.3%), abdominal pain (7.9%), hypertension (19.4%). These symptoms experienced are significantly higher among consumers of these drinks compared to controls. Witnesses consume either energy drinks or sugary drinks. Discussion/Conclusion: That frequent consumption of energy drinks may pose a risk and a danger to the health of consumers, hence the need for awareness especially young people against their effects. Public health organizations must also keep a close watch on this new trend.
Impact of Eating Habits and Lifestyle on the Oral Health Status of a Casablanca’s Academic Population  [PDF]
Houriya Mestaghanmi, Ali Labriji, Imane M’Touguy, Fatima Zahra Kehailou, Said Idhammou, Nabil Kobb, Fatema Zahra Mahfoud, Ahmadaye Ibrahim Khalil, Souad El Amrani
Open Access Library Journal (OALib Journal) , 2018, DOI: 10.4236/oalib.1104967
Abstract:
Introduction: Bad eating habits can have serious impact on oral health. Objec-tives: To study the impact of eating habits and dental hygiene practices on the dental status of students. Methods: Cross-sectional study of 400 students aged 17 and more, from the Ben M’Sik Sciences Faculty. A questionnaire on the so-cio-economic level of the parents, the eating habits, the means of hygiene and the oral health status has been filled in anonymously by the respondents. Uni-variate and multivariate descriptive and comparative analyzes were per-formed by the software SPSS 21. Results: The population’s average age is 20 ± 1.59 years old consisted of 55% of boys and 45% of girls. The breakfast is consumed by 67% of students. 39.58% respondents consume sweetened drinks during the meals and 60% at the end of meals and 66% are snacking during the day. 92% of students say they brush their teeth. The brushing time varies between 1 and 3 minutes. 37% of students do never consult a dentist and 63% in case of dental problems. The prevalence of caries is 66%. There is a positive association between the prevalence of tooth decay and certain eating habits (sweet things consumption (p = 0.08), cakes (p = 0.018) and chocolate (p = 0.019) outside of meals). However, this correlation is negative, when the consumption of these foods is done during meals (p > 0.74). On the other hand, there was no correlation between alcohol consumption and presence of caries (p = 0.172), tobacco consumption (p = 0.319), and socioeconomic status parents (p = 0.733). Conclusion: Oral hygiene and regular monitoring by a dentist with healthy eating habits can have a significant impact on the oral status of students.
EFFECTS OF ALUMINIUM CHLORIDE ON HISTOLOGICAL STRUCTURE OF LUNGS, KIDNEY AND INTESTINE IN PREGNANT RATS AND THEIR OFFSPRING
MESTAGHANMIHouriya,Houriya, EL AMRANI,M’TOUGUY Imane,SAILE3 Rachid
Technologies de Laboratoire , 2013,
Abstract: Chlorure d’aluminium, foetus, intestin, reins, poumons, rates gestantes.Summary: The aim of our study is to elucidate the effects of the administration of different doses of aluminium chloride during 9-13 gestation day on organs histology of pregnant rats and their offspring.We have noted that in pregnant rats, there is a change on the histological structure of intestine especially on enterocytes, nuclei and basal lamina.In kidney, we have observed a lesion in proximal and distal tubes. In lungs, AlCl3 may decrease the alveolar diameter, an inflammation with necrosis of pneumocytes notably with the dose of 200 mg of AlCl3 /kg/day.In fetuses, AlCl3 may cause a detachment between the intestinal epithelium and the underlying conjonctif and a necrosis of renal and pulmonary cells.AlCl3 has an effect more marked in mother than their fetuses. This indicates that the placenta is a selective barrier towards some components.
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