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Nonexistence of Continuous Peaking Functions
Jiye Yu
Mathematics , 1995,
Abstract: We construct a smoothly bounded pseudoconvex domain such that every boundary point has a p.s.h. peak function but some boundary point admits no (local) holomorphic peak function.
On a conjecture in Moreau-Yosida approximation of a nonsmooth convex function
Defeng Sun,Jiye Han
Chinese Science Bulletin , 1997, DOI: 10.1007/BF02883049
Abstract:
Effects of acute hypoxia on responses of rod- and cone-driven horizontal cells in carp retinain vivo
Jiye Wei,Xiongli Yang
Chinese Science Bulletin , 1997, DOI: 10.1007/BF02882478
Abstract:
An Indirect Immunoassay for Detecting Antigen Based on Fluorescence Resonance Energy Transfer  [PDF]
Peihui Yang, Shuguang Yao, Wei Wei, Jiye Cai
American Journal of Analytical Chemistry (AJAC) , 2011, DOI: 10.4236/ajac.2011.24058
Abstract: An indirect immunoassay for detecting antigen was developed. It was based on fluorescence resonance energy transfer (FRET) and quenching of gold nanoparticles. Bovine serum albumin (BSA) was chosen as model antigen. Fluorescein isothiocyanate (FITC) was attached to anti-BSA antibody (anti-BSA–FITC) as FRET donor, while BSA was conjugated to gold nanoparticles (GNPs–BSA) as FRET acceptor. The formation of anti-BSA–BSA immunocomplex resulted in the FRET between anti-BSA–FITC and GNPs–BSA. Thus, the fluorescence of FRET donor was quenched, and the decreasing fluorescence intensity responded linearly to the concentration of acceptor within the linear range. The concentration of BSA we obtained according to the stoichiometric ratio between BSA and GNPs. Following this approach, we were able to specifically detect BSA. The detection limit for BSA was 0.5 nM and the linear range of the assay was 2.9 - 43.5 nM. It had been successfully applied to specific detection of BSA in serum samples.
Effects of acute hypoxia on responses of rod- and cone-driven horizontal cells in carp retina in vivo

Jiye Wei,Xiongli Yang,

科学通报(英文版) , 1997,
Abstract:
Saliva Ontology: An ontology-based framework for a Salivaomics Knowledge Base
Jiye Ai, Barry Smith, David T Wong
BMC Bioinformatics , 2010, DOI: 10.1186/1471-2105-11-302
Abstract: We define the Saliva Ontology (SALO; http://www.skb.ucla.edu/SALO/ webcite) as a consensus-based controlled vocabulary of terms and relations dedicated to the salivaomics domain and to saliva-related diagnostics following the principles of the OBO (Open Biomedical Ontologies) Foundry.The Saliva Ontology is an ongoing exploratory initiative. The ontology will be used to facilitate salivaomics data retrieval and integration across multiple fields of research together with data analysis and data mining. The ontology will be tested through its ability to serve the annotation ('tagging') of a representative corpus of salivaomics research literature that is to be incorporated into the SKB.Saliva (oral fluid) is an emerging biofluid for non-invasive diagnostics used in the detection of human diseases. The need to advance saliva research is strongly emphasized by the National Institute of Dental and Craniofacial Research (NIDCR), and is included in the NIDCR's 2004-2009 expert panel long-term research agenda [1]. The ability to monitor health status, disease onset, progression, recurrence and treatment outcome through non-invasive means is highly important to advancing health care management. Saliva is a perfect medium to be explored for personalized individual medicine including diagnostics, offering a non-invasive, easy to obtain means for detecting and monitoring diseases. Saliva testing potentially allows the patient to collect their own saliva samples at home, yielding convenience for the patient and savings in health costs, and facilitating multiple sampling. Specimen collection is less objectionable to patients and easier in children and elderly individuals.Due to these advantages, finding biomarkers in saliva for the detection of serious illnesses such as cancers has been on the national healthcare agenda for several years, and the National Cancer Institute has accordingly recognized saliva as a promising source for cancer biomarkers [2]. A mandate in the Government
A trust region algorithm for bilevel programing problems
Guoshan Liu,Jiye Han,Shouyang Wang
Chinese Science Bulletin , 1998, DOI: 10.1007/BF03182744
Abstract: A trust region algorithm is proposed for solving bilevel programming problems where the lower lwel programming problem is a strongly convex programming problem with linear constraints. This algorithm is based on a trust region algorithm for nonsmooth unconstrained optimization problems, and its global convergence is also proved.
Cold Induces Micro- and Nano-Scale Reorganization of Lipid Raft Markers at Mounds of T-Cell Membrane Fluctuations
Yong Chen, Jie Qin, Jiye Cai, Zheng W. Chen
PLOS ONE , 2009, DOI: 10.1371/journal.pone.0005386
Abstract: Whether and how cold causes changes in cell-membrane or lipid rafts remain poorly characterized. Using the NSOM/QD and confocal imaging systems, we found that cold caused microscale redistribution of lipid raft markers, GM1 for lipid and CD59 for protein, from the peripheral part of microdomains to the central part on Jurkat T cells, and that cold also induced the nanoscale size-enlargement (1/3- to 2/3-fold) of the nanoclusters of lipid raft markers and even the colocalization of GM1 and CD59 nanoclusters. These findings indicate cold-induced lateral rearrangement/coalescence of raft-related membrane heterogeneity. The cold-induced re-distribution of lipid raft markers under a nearly-natural condition provide clues for their alternations, and help to propose a model in which raft lipids associate themselves or interact with protein components to generate functional membrane heterogeneity in response to stimulus. The data also underscore the possible cold-induced artifacts in early-described cold-related experiments and the detergent-resistance-based analyses of lipid rafts at 4°C, and provide a biophysical explanation for recently-reported cold-induced activation of signaling pathways in T cells. Importantly, our fluorescence-topographic NSOM imaging demonstrated that GM1/CD59 raft markers distributed and re-distributed at mounds but not depressions of T-cell membrane fluctuations. Such mound-top distribution of lipid raft markers or lipid rafts provides spatial advantage for lipid rafts or contact molecules interacting readily with neighboring cells or free molecules.
Probing molecular interaction between transferrin and anti-transferrin by atomic force microscope
Zhiwen Zheng,Peihui Yang,Gucheng Zeng,Jiye Cai
Chinese Science Bulletin , 2006, DOI: 10.1007/s11434-006-0405-0
Abstract: The interaction between transferrin (Tf) and its antibody was investigated by atomic force microscope. Tf-antibody was immobilized on the Au-coated glass slide, and the specific combination between antibody and antigen was also characterized by AFM. The results showed that holo-transferrin was jogged with anti-transferrin, and binded anti-transferrin more tightly than apo-transferrin. The force-distance curves revealed that the affinity of anti-transferrin and holo-transferrin was much stronger than that of apo-transferrin.
CONVERGENCE PROPERTIES OF THE BROYDEN''S FAMILY WITH A NEW LINE SEARCH
结合一种新搜索的Broyden算法类的全局收敛性

Liu Guanghui,Han Jiye,
刘光辉
,韩继业

系统科学与数学 , 1998,
Abstract: The number of translation equivalence classes of linear recurring m-arrays witha diagonal fundamental period matrix was given in 1]. In this paper, we determine separatelythe enumeration of linear recurring m-arrays with (1) an arbitrary possib
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