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Desprendimiento postquirúrgico de la membrana de descemet: a propósito de un caso
Sevillano,C.; Viso,E.; Millán-Rodríguez,A.C.;
Archivos de la Sociedad Espa?ola de Oftalmología , 2008, DOI: 10.4321/S0365-66912008000900008
Abstract: case: a case of descemet?s membrane detachment after cataract surgery successfully treated with an injection of sulphur hexafluoride 20% is presented. discussion: possible pathogenic mechanisms and available therapeutic options are discussed. we highlight the need for prophylactic measures and the importance of an early detection to prevent further damage.
Desprendimiento postquirúrgico de la membrana de descemet: a propósito de un caso Descemet's membrane detachment as a complication of cataract surgery
C. Sevillano,E. Viso,A.C. Millán-Rodríguez
Archivos de la Sociedad Espa?ola de Oftalmología , 2008,
Abstract: Caso clínico: Se presenta un caso de desprendimiento de la membrana de Descemet tras cirugía de la catarata mediante facoemulsificación tratado con éxito utilizando SF6 al 20% intracameral. Discusión: Se exponen los posibles mecanismos etiopatogénicos y se comentan las distintas opciones terapéuticas. Enfatizamos la necesidad de adopción de medidas preventivas de este trastorno y de la importancia de su detección inmediata para evitar complicaciones adicionales. Case: A case of Descemet’s membrane detachment after cataract surgery successfully treated with an injection of sulphur hexafluoride 20% is presented. Discussion: Possible pathogenic mechanisms and available therapeutic options are discussed. We highlight the need for prophylactic measures and the importance of an early detection to prevent further damage.
Sarcoma granulocítico conjuntival en leucemia mieloblástica aguda M1
Méndez-Cepeda,P.; Millán-Rodríguez,A.C.; Dios,E.; álvarez,C.; Sevillano,C.;
Archivos de la Sociedad Espa?ola de Oftalmología , 2012,
Abstract: clinical case: a 69-year-old man with a history of acute myeloblastic leukemia-m1 presented with bilateral conjunctival injection. ophthalmological examination revealed lesions located at the upper tarsal conjunctiva of the right eye and lower tarsal conjunctiva of both eyes. histological and immunohistochemical studies confirmed conjunctival myeloid sarcoma. the patient died due to multiorgan failure three months later. discussion: extramedullary recurrence of leukemia can appear as an ocular manifestation that brings about a recurrence of the leukemia, leading to a poor prognosis.
Uveítis intermedia por virus linfotropo humano de células T Tipo 1 Intermediate uveitis due to human T-cell lymphotropic virus type 1
A.C. Millán-Rodríguez,C. Fernández-Cid,M. García-Campello,C. Sevillano
Archivos de la Sociedad Espa?ola de Oftalmología , 2012,
Abstract: Caso clínico: Se presenta el caso de una mujer de 66 a os con uveítis intermedia bilateral y debilidad progresiva de miembros inferiores. En estudio serológico se detecta infección por virus linfotropo humano de células T tipo 1 (VLHT-1), siendo diagnosticada la paciente de paraparesia espástica tropical y uveítis intermedia por VLHT-1. La paciente evolucionó favorablemente con tratamiento corticoideo oral. Discusión: Se comenta la clínica y la epidemiología de la infección por VLHT-1. Se recomienda la realización de serología para el virus en uveítis intermedias no filiadas en inmigrantes de áreas endémicas o con síntomas neurológicos. Case report: The case of a 66-year-old woman with intermediate uveitis in both eyes and progressive weakness of lower limbs is reported. A human T-lymphotropic virus type 1 (HTLV-1) infection was detected in the serological study, with the patient being diagnosed with tropical spastic paraparesis and HTLV-1 intermediate uveitis. The patient made good progress with oral steroid treatment. Discussion: The clinical and epidemiological aspects of HTLV-1 infection are discussed. We recommend a serological determination of the virus in intermediate uveitis of unknown origin in people from endemic areas or with neurological symptoms.
Sarcoma granulocítico conjuntival en leucemia mieloblástica aguda M1 Conjunctival myeloid sarcoma in acute myeloblastic leukemia-M1
P. Méndez-Cepeda,A.C. Millán-Rodríguez,E. Dios,C. álvarez
Archivos de la Sociedad Espa?ola de Oftalmología , 2012,
Abstract: Caso clínico: Varón de 69 a os diagnosticado de leucemia mieloblástica aguda M1 en remisión completa, remitido a Oftalmología por cuadro de ojo rojo no doloroso. Biomicroscópicamente se observan lesiones sobreelevadas asalmonadas en conjuntiva tarsal superior de ojo derecho e inferior de ambos ojos. Mediante estudios histológicos e inmunohistoquímicos se confirma recidiva extramedular en forma de sarcoma mieloide en conjuntiva. El paciente fallece a los 3 meses de un fallo multiorgánico. Discusión: La recidiva extramedular de una leucemia puede presentarse como una manifestación ocular que conlleva una recurrencia de la leucemia, siendo esta de mal pronóstico. Clinical case: A 69-year-old man with a history of acute myeloblastic leukemia-M1 presented with bilateral conjunctival injection. Ophthalmological examination revealed lesions located at the upper tarsal conjunctiva of the right eye and lower tarsal conjunctiva of both eyes. Histological and immunohistochemical studies confirmed conjunctival myeloid sarcoma. The patient died due to multiorgan failure three months later. Discussion: Extramedullary recurrence of leukemia can appear as an ocular manifestation that brings about a recurrence of the leukemia, leading to a poor prognosis.
Small Renal Masses: Incidental Diagnosis, Clinical Symptoms, and Prognostic Factors
F. M. Sánchez-Martín,F. Millán-Rodríguez,G. Urdaneta-Pignalosa,J. Rubio-Briones,H. Villavicencio-Mavrich
Advances in Urology , 2008, DOI: 10.1155/2008/310694
Abstract: Introduction. The small renal masses (SRMs) have increased over the past two decades due to more liberal use of imaging techniques. SRMs have allowed discussions regarding their prognostic, diagnosis, and therapeutic approach. Materials and methods. Clinical presentation, incidental diagnosis, and prognosis factors of SRMs are discussed in this review. Results. SRMs are defined as lesions less than 4 cm in diameter. SRM could be benign, and most malignant SMRs are low stage and low grade. Clinical symptoms like hematuria are very rare, being diagnosed by chance (incidental) in most cases. Size, stage, and grade are still the most consistent prognosis factors in (RCC). An enhanced contrast SRM that grows during active surveillance is clearly malignant, and its aggressive potential increases in those greater than 3 cm. Clear cell carcinoma is the most frequent cellular type of malign SRM. Conclusions. Only some SRMs are benign. The great majority of malign SRMs have good prognosis (low stage and grade, no metastasis) with open or laparoscopic surgical treatment (nephron sparing techniques). Active surveillance is an accepted attitude in selected cases.
Uveítis intermedia por virus linfotropo humano de células T Tipo 1
Millán-Rodríguez,A.C.; Fernández-Cid,C.; García-Campello,M.; Sevillano,C.; Fernández-Vila,P.C.;
Archivos de la Sociedad Espa?ola de Oftalmología , 2012,
Abstract: case report: the case of a 66-year-old woman with intermediate uveitis in both eyes and progressive weakness of lower limbs is reported. a human t-lymphotropic virus type 1 (htlv-1) infection was detected in the serological study, with the patient being diagnosed with tropical spastic paraparesis and htlv-1 intermediate uveitis. the patient made good progress with oral steroid treatment. discussion: the clinical and epidemiological aspects of htlv-1 infection are discussed. we recommend a serological determination of the virus in intermediate uveitis of unknown origin in people from endemic areas or with neurological symptoms.
Disminución de agudeza visual, primer síntoma de un tumor medular Visual acuity loss, the initial sympton of a spinal cord neoplasm
A.C. Millán-Rodríguez,V. Lázaro-González,E. Dios-Castro,A. R. Regal
Archivos de la Sociedad Espa?ola de Oftalmología , 2008,
Abstract: Caso clínico: Se presenta el caso de una mujer de 46 a os con disminución de agudeza visual en el ojo derecho y papiledema, con dilatación ventricular en la Resonancia Magnética Nuclear (RMN) cerebral. En la punción lumbar se detectó hiperproteinorraquia. La RMN medular reveló la presencia de una neoplasia de la médula espinal. La paciente recuperó la agudeza visual tras la extirpación quirúrgica del tumor, que resultó ser un neurilemoma. Discusión: Se comenta la presentación ocular y la fisiopatología de la hipertensión intracraneal en el tumor espinal. Asimismo se destaca la importancia del diagnóstico etiológico del papiledema. Case report: A 46-year-old woman, who presented with right visual acuity loss, was found to have papilledema, and subsequently shown to have ventricular dilatation in a cerebral Magnetic Resonance Imaging (MRI) assessment. Elevated protein levels were found in the cerebrospinal fluid. Spinal MRI revealed the presence of a spinal cord neoplasm. After surgical removal of the tumor, which turned out to be a neurilemmoma, the patient’s visual acuity was restored. Discussion: The ocular presentation and the relationship between intracranial hypertension and spinal tumors are discussed. Likewise, the importance of considering the various causes of papilledema is emphasized.
Trasplante de células progenitoras hematopoyéticas en síndromes mielodisplásicos
León-Rodríguez, Eucario;
Revista de investigación clínica , 2005,
Abstract: myelodisplastic syndromes (mds) are clonal hematopoietic disorders, characterized by ineffective hemopoiesis resulting in single or multiple lineages and a high risk of conversion to acute leukemia. currently, the only established therapy with curative potential for mds is a hemopoietic stem cell transplant (hsct). their results are determined by the type of mds, age at the bmt and the score according to the international index. in the main studies the disease-free survival (dfs) were 35-43%, relapse 20 to 39% and transplantation-related mortality (trm) 36-45%. hsct offers best results in goods prognosis mds (refractory anemia, refractory anemia with ring sideroblasts) with dfs of 53-72% and 13% of relapse, in contrast with the advanced mds (refractory anemia with blast in excess (areb), areb in transformation and secondary acute leukemia) where the dfs is about 33%, the relapse 23-34% and mrt 37-60%. the hsct from unrelated donor is an option for patients that do not an hla-matched related donor, with a 30% of dfs, but with a mrt up to 58%. the hsct with regimens of low intensity (minitransplants) for aged patients are feasible but their efficacy has not yet been determined.
Por qué y cómo hemos de analizar los cálculos urinarios
Gràcia-Garcia,S.; Millán-Rodríguez,F.; Rousaud-Barón,F.; Monta?és-Bermúdez,R.; Angerri-Feu,O.; Sánchez-Martín,F.; Villavicencio-Mavrich,H.; Oliver-Samper,A.;
Actas Urológicas Espa?olas , 2011, DOI: 10.4321/S0210-48062011000600008
Abstract: context: there is heterogeneity of criteria on the utility of urinary stone analysis as well as on which is the most suitable methodology. this review presents the analysis of the lithiasis using the morphoconstitutional analysis technique based on the combination of the stereoscopic microscopy (sm) with infrared study (irs). summary of the evidence: there are many techniques to analyze the stone: chemical analysis, electron microscopy, x-ray diffraction, sm and irs. reviewing each one of these techniques and through the study of several clinical cases, this review shows the usefulness of stone analysis and the pros and cons of each one of the mentioned techniques. furthermore, it can be clearly seen how the morphoconstitutional analysis is the one that offers the most useful clinical information to the urologist. in addition, classification of the lithiasis based on this method and its clinical correlation with patients is presented. conclusions: using the morphoconstitutional study to analyze the stone offers more information than the other techniques and it makes it possible to establish a stone classification of important clinical and diagnostic utility.
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