Background: Vitamin D deficiency has been targeted
as a cause of the increased incidence of allergic rhinitis. Many factors,
including sun exposure, influence vitamin D levels. Indonesia is a country with
abundant sunshine exposure throughout the year; therefore, Indonesian residents
are not expected to have inadequate vitamin D levels. Objective: This study
aimed to investigate whether vitamin D deficiency levels are correlated with disease spectrum among allergic
rhinitis patients.
Material and Method: A cross-sectional study was conducted
in the Rhino-Allergy ORL-HNS Clinic at Dr. Hasan Sadikin General Hospital in
Bandung, Indonesia, from March-June 2016. All subjects underwent skin prick
tests and serum 25-hydroxy vitamin D levels examination. To measure the association between vitamin D
deficiency level and severity of allergic rhinitis, a Rank-Spearman correlation
test was used and significant level was determined when the p-value is <0.05.
Results: A total of 46 allergic rhinitis patients (19 males, 27 females, aged
28.3 ± 6 years) were included in this study. 63% of allergic rhinitis patients had a severe
vitamin D deficiency and 50% of them classified as having persistent
moderate-severe based on ARIA-WHO classification. Vitamin
D deficiency was found to be significantly correlated with severity of allergic
rhinitis status (rs = ?0.321; p = 0.005). Conclusion: We found vitamin D deficiency was correlated
with allergic rhinitis classification and a significant proportion of allergic
rhinitis patients showed a severe vitamin D
deficiency.
Cite this paper
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