Background: In the
Democratic Republic of Congo, the use of Prevention of Transmission of Human
Immunodeficiency Virus infection from mother to child is still very low. Objective:
The objective of this study was to estimate the prevalence of infants born from
HIV-positive mother in different centers in Kinshasa. Methods: This study is a
retrospective cohort of at least 2 years on the records of mother-child couple
followed in 8 centers of Kinshasa. Based on a sample survey form with specific
criteria, some files were selected. Results: The record keeping of all centers
was estimated at 70% on average; the most represented age group was from 26 to
35 years with 102 women (54%) out of 190. Forty-five percent (45%) of pregnant
women started pre-natal consultation (CPN) in the 2nd trimester of pregnancy. All mothers had been
diagnosed with 3 Rapid Diagnostic Tests (RDT). The majority of women were under: AZT 3TC NVP
and CTX and 139 (73%) women were diagnosed at stage 1 of HIV infection according
to WHO’s standard. One hundred new born were male. Seventy-eight newborns
weighed between 2.01 and 3.00 kg at
birth. Ninety seven percent of newborns were treated at birth. Ninety-one
children who were on Nevirapine syrup; six of them were not put on treatment.
Ninety five percent of newborns were diagnosed HIV-negative 9 months after
birth by PCR; 2% of
children were undiagnosed as a result of refusal and 3% of children had undetermined
serology. This gives a mother-to-child transmission rate of 2% at 9 months of
birth for the centers of Kinshasa. Conclusion: Despite the insufficient
coverage of the PMTCT service in our community, the centers in Kinshasa respond
to the PMTCT approach and the transmission rate in the 8 centers of 4 districts
of Kinshasa is 2%.
Cite this paper
Chuga, D. , Bulanda, B. I. , Kabasele, J. Y. D. , Okonda, M. O. , Bongenya, B. I. and Kamangu, E. N. (2018). Vertical Transmission Rate of HIV from Seropositive Mothers Followed in the Different Care Centers in Kinshasa from 2010 to 2015. Open Access Library Journal, 5, e4769. doi: http://dx.doi.org/10.4236/oalib.1104769.
Ministère du Plan et Suivi de la Mise en oeuvre de la Révolution de la Modernité et Ministère de la Santé Publique and République Démocratique du Congo (2014) Enquête Démographique et de Santé (EDS) 2013-2014: Rapport Annuel Préliminaire sur la Prévalence du VIH.
Programme National de Lutte contre le VIH/SIDA et les Infections Sexuellement Transmissible (PNLS) and Ministère de la Santé Publique and République Démocratique du Congo (RDC) (2016) Rapport Annueld’ Activité 2015.
Programme National de Lutte contre le VIH/SIDA et les Infections Sexuellement Transmissible (PNLS) and Ministère de la Santé Publique and République Démocratique du Congo (RDC) (2014) Revue Nationale: Programme National de lutte contre le VIH et le SIDA innové en RDC; un accès au traitement antirétroviral simplifié et de qualité.
Bongenia, I.B., Ilombo, L.L., Botomwito, T.H., Bulanda, I.B., Kamangu, N.E., Lusakibanza, M. and Mesia, K.G. (2014) Fréquence du Suivi des Paramètres Biologiques des Patients sous Antirétroviraux à Kinshasa: Cas de l’Hopital Provincial Général de Référence. Journal de Recherche Biomédicale, 1, 1-6.
Bongenia, I.B., Bukongo, N.R., Kabasele, D.J.Y., Okonda, O.M., Chuga, D., Botomuito, T.H., Bulanda, I.B. and Kamangu, N.E. Prévalence des infections opportunistes chez les enfants infectés par le VIH de 0 à 12 ans à Kinshasa: Cas de l’hopital pédiatrique de Kalembe Lembe.
Kimbala, J., Mukuku, O., Tshibangu, C.K., Kapend, L., Numbi, O.L., Muteba, F., Mande, J., Ngoy, F.K., Lufwa, D., Matembo, P. and Kizonde, J. (2016) Prévention de la transmission du VIH de la mère à l’enfant à Lubumbashi en RDC: Résultats de 6 ans de pratique dans 5 maternités de référence. Médecine d’Afrique Noire, 63, 111.
Mwembo-Tambwe, N.A., Kalenga, P., Donnen, P., Chenge, M.F., Hulet, P., Dramaix, M. and Buekens, P. (2012) Delivery with Unknown HIV Serostatus in Lubumbashi: Proportion and Determinants. The Pan African Medical Journal, 12, 25-33.
Kanteng, A.W., Assumani, N.A., ShongoYa, P.M., Yansenda, M.P., Mutoke, N.G., Ilunga, M.P. and Luboya, N.O. (2013) Prévalence et facteurs de risque liés à la transmission verticale du VIH. Cas du centre PTME des cliniques universitaires de Lubumbashi. Révue Médicales des Grands Lacs, 4, 12.
Djadou, K.E., Ocloo, A., Dokounor, D., Agbodjan-Djoussou, O., Akapossa, A. and Atakouma, D.Y. (2006) Prise en charge des enfants nés des mères infectés par le VIH au Centre Hospitalier régional de Tsévié, Togo. Courte Note, #3020.
Ramazani, B.N. (2013) The Management of Opportunistic Infections in Children from 0 to 12 Years of Age Diagnosed HIV-Positive from 2007 to 2013, Born from HIV-Positive Mothers at Kalembelembe Pediatric Hospital City of Kinshasa. Dissertation, Technological University Bel Campus, Kinshasa.